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001 978-3-030-33656-1
003 DE-He213
005 20250526092115.0
007 cr nn 008mamaa
008 200220s2020 sz | s |||| 0|eng d
020 _a9783030336561
_9978-3-030-33656-1
024 7 _a10.1007/978-3-030-33656-1
_2doi
050 4 _aRM300-666
072 7 _aMMG
_2bicssc
072 7 _aMED071000
_2bisacsh
072 7 _aMKG
_2thema
082 0 4 _a615
_223
245 1 0 _aGood Research Practice in Non-Clinical Pharmacology and Biomedicine
_h[electronic resource] /
_cedited by Anton Bespalov, Martin C. Michel, Thomas Steckler.
250 _a1st ed. 2020.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2020.
300 _aX, 423 p. 34 illus., 21 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aHandbook of Experimental Pharmacology,
_x1865-0325 ;
_v257
505 0 _a1. Quality in Non-GxP Research Environment -- 2. Guidelines & Initiatives for Good Research Practice -- 3. Learning from principles of evidence-based medicine to optimize nonclinical research practices -- 4. General Principles of Preclinical Study Design -- 5. Resolving the tension between exploration and confirmation in preclinical biomedical research -- 6. Blinding and Randomization -- 7. Out of control? Managing baseline variability in experimental studies with control groups -- 8. Quality of Research Tools -- 9. Genetic background and sex: impact on generalizability of research findings in pharmacology studies -- 10. Building robustness intro translational research -- 11. Minimum information and quality standards for conducting, reporting, and organizing in vitro research -- 12. Minimum Information in In Vivo Research -- 13. A reckless guide to P-values: Local evidence, global errors -- 14. Electronic Lab Notebooks and Experimental Design Assistants -- 15. Data storage -- 16. Design of meta-analysis studies -- 17. Publishers’ responsibilities in promoting data quality and reproducibility -- 18. Quality governance in biomedical research -- 19. Good Research Practice – Lessons from Animal Care & Use -- 20. Research collaborations and quality in research: foes or friends? -- 21. Costs of implementing quality in research practice.
506 0 _aOpen Access
520 _aThis open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.
650 0 _aPharmacology.
650 0 _aNeurosciences.
650 0 _aCardiology.
650 0 _aOncology.
650 1 4 _aPharmacology.
650 2 4 _aNeuroscience.
650 2 4 _aCardiology.
650 2 4 _aOncology.
700 1 _aBespalov, Anton.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aMichel, Martin C.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aSteckler, Thomas.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9783030336554
776 0 8 _iPrinted edition:
_z9783030336578
776 0 8 _iPrinted edition:
_z9783030336585
830 0 _aHandbook of Experimental Pharmacology,
_x1865-0325 ;
_v257
856 4 0 _uhttps://doi.org/10.1007/978-3-030-33656-1
912 _aZDB-2-SBL
912 _aZDB-2-SXB
912 _aZDB-2-SOB
999 _c46
_d46